University
of Pittsburgh Carnegie Mellon University

Joint CMU-Pitt Ph.D. Program in Computational Biology

Robert F. Murphy and Ivet Bahar, Directors

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Computational Genomics Specialization Area

Computational Genomics entails efforts to digest the daunting quantity of genomic and proteomic data now available by systematic development and application of probability and statistics theories, information technologies and data mining techniques. Linguistics methods are viewed as promising tools towards elucidating sequence-structure-function relations, and complementing computational genomics studies. Computational genomics targets understanding gene/protein function, identifying and characterizing cellular regulatory networks and discerning the link between genes and diseases. Discovery and processing of this information is pivotal in the development of novel gene therapy strategies and tools.

Required Life Science Elective

CMU 03-730Advanced Genetics
CMU 03-740Advanced Biochemistry
CMU 03-741Advanced Cell Biology
CMU 03-742Molecular Biology of Eukaryotes
Pitt BIOSC 2100Advanced Topics in Cell Biology

Required Quantitative Elective (one of the following)

Pitt BIOINF 2101 Probabilistic Models for Computer-Based Decision Support
Pitt BIOST 2015Elements of Statistical Learning
Pitt BIOST 2063Bayesian and Empirical Statistical Methods
Pitt BIOST 2064Bayesian and Empirical Bayes Computational Methods
Pitt CS 2550Principles of Database Design
CMU 15-750Algorithms
CMU 15-853Algorithms in the Real World
CMU 10-702Statistical Machine Learning
CMU 10-708Probabilistic Graphical Models
CMU 36-705Intermediate Statistics

Specialization Electives (two of the following)

Pitt BIOINF 2054Statistical Foundations for Bioinformatics Data Mining
Pitt BIOINF 2055Practical Analysis of High-Throughput Genomic & Proteomic Data
Pitt MSMPHL 3315Bioinformatics of Cancer Biology & Therapeutics
Pitt BIOST 2070Statistical Methods and Data Mining in Microarray Analysis
Pitt MSCBIO 2020Bioinformatics of Gene Regulation
CMU 03-711Computational Molecular Biology and Genomics