Curriculum: Computational Structural Biology Specialization Area
Computational Structural Biology aims at establishing biomolecular sequence-structure-function relations using fundamental principles of physical sciences in theoretical models and simulations of structure and dynamics. After the advances in complete genomes sequencing, it became evident that structural information is needed for understanding the origin and mechanisms of biological interactions, and designing/controlling function. Computational Structural Biology emerged as a tool for efficient identification of structure and dynamics in many applications. Major research topics include protein folding, protein dynamics with emphasis on large complexes and assemblies, protein-protein, protein-ligand and protein-DNA interactions and their functional implications. Drug design and protein engineering represent applications of note.
Required Life Sciences Elective (3 credits/9 units)
| Pitt MSMBPH-2001 | Molecular Biophysics I |
Macromolecular Structure and Function |
Specialization Electives (3 credits/9 units)
CMU 15-879A |
Algorithms for Computational Structural Biology |
Computational Structural Biology II |
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Advanced Algorithms for Computational Structural Biology |
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Statistical Mechanics |
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Principles of Polymer Engineering |
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Quantum Mechanics and Kinetics |
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Thermodynamics & Statistical Mechanics |
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Introduction to Modern Computational Chemistry |
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Molecular Modeling and Graphics |
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Quantitative Elements of Cell Form and Movement |
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Principles of Pharmacology |
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Drug Discovery |
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Molecular Pharmacology |
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Computational Physics |
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Statistical Physics |
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Molecular Modeling and Computational Chemistry |

